FAKTOR – FAKTOR YANG MEMPENGARUHI KEJADIAN KEMATIAN PADA PASIEN ACUTE RESPIRATORY DISTRESS SYNDROME DI ICU

Authors

  • Ika L. Sianturi Universitas Methodist Indonesia
  • Jadeny Sinatra Universitas Methodist Indonesia
  • Ronald Tambunan

Keywords:

acute respiratory distress syndrome, mortality, ICU

Abstract

Background : Acute Respiratory Distress Syndrome (ARDS) is a critical illness caused by infection or trauma to the lungs that requires treatment in the ICU with a mortality rate that can reach 40 to 60%. Deaths from ARDS are influenced by various factors. In terms of reducing the mortality of ARDS patients, it is necessary to know the factors that influence it. Various studies regarding the factors that influence the mortality of ARDS patients still show different results. This study aims to determine the factors that influence the incidence of death in patients with acute respiratory distress syndrome in ICU.

Methods : This type of research uses the method of literature study or literature review with a maximum time span of journal publishing of 5 years from 2015 to 2020. The population in this study were ARDS patients.

Conclusion : The results of this study indicate that the factors that influence the incidence of death in ARDS patients in the ICU are age, gender, comorbidities (pneumonia, COPD and sepsis) and the use of a ventilator. It can be concluded that the factors that most dominantly influence the incidence of death in ARDS patients are the factors associated with sepsis.

References

Mackay A, Haddad M. Acute lung injury and acute respiratory distres syndrome. Cont Edu Anaesth Crit Care and Pain. 2009; 9(5): 152–156.

Bernard GR, Artigas A, Brigham KL, et al. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med. 2016;149(3 pt 1):818-824.

Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med. 2000;342(18):1334-1349.

Pham T, Rubenfeld G. The Epidemiology of Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2017;195:860–70.

Fanelli V, Vlachou A, Simonetti U, Slutsky AS, Zhang H. Acute respiratory distress syndrome: new definition, current and Fanelli V, future therapeutic options. Journal of Thoracic Disease. 2013, 5(3): 326-334.

Amin Z, Purwoto J. Acute Respiratory Distress Syndrome (ARDS). In: Sudoyo AW, Setiyohadi B, Alwi I. Buku Ajar Ilmu Penyakit Dalam. Balai Penerbit FK UI; 2009. Hal: 4072-4079.

Lee WL, Slutsky AS. Hypoxemic respiratory failure, including acute respiratory distress syndrome. In: Mason RJ, Murray JF, Broaddus VC, Nadel JA, eds. Textbook of respiratory medicine. 4th ed. Philadelphia: Elsevier Saunders; 2005.p.2352-78.

Amato M, Meade M, Slutsky A, Brochard L, Costa EL, Schoenfeld DA, dkk. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med 2015;372:747– 55.

ARDS Definition Task Force. Acute Respiratory Distress Syndrome, The Berlin Definition. JAMA. 2012;307(23).

Haro C, Martin-Loeches I, Torrents E& Artigas A. Acute respiratory distress syndrome: prevention and early recognition. Annals of Intensive Care 2013, :11.

Saguil A& Fargo M. Acute Respiratory Distress Syndrome: Diagnosis and Management. Am Fam Physician. 2012;85(4):352-358.

Fanelli V, Vlachou A, Ghannadian S, Simonetti U, Slutsky AS, Zhang H. Acute Respiratory Distress Syndrome: New definition, Current, and Future Therapeutic Options. Journal of Thoracic Disease. 2013; 5(3): 326-34.

Harman EM. Acute Respiratory Distress Syndrome. Medscape. 2012. Accessed on May 9th, 2012. Available at: http://emedicine. medscape.com/article/165139- overview.

Parsons PE. Acute respiratory distress syndrome. In: Hanley ME, Welsh CH, eds. Current diagnosis and treatment in pulmonary medicine. New York: Lange Medical Books/McGraw-Hill; 2003.p.1616.

Lee WL, Slutsky AS. Hypoxemic respiratory failure, including acute respiratory distress syndrome. In: Mason RJ, Murray JF, Broaddus VC, Nadel JA, eds. Textbook of respiratory medicine. 4th ed. Philadelphia: Elsevier Saunders; 2005.p.2352-78.

Matthay MA, Zemans RL. The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment. Annu Rev Pathol. 2011;6:147-63.

Pierrakos C, Karanikolas M, Scoletta S, Karamouzos V, Velissaris D. Acute Respiratory Distress Syndrome: Pathophysiology and Theurapeutic Options. J. Clin Med Res. 2011;4(1):7-16.

Sigurdsson MI, Sigvaldason K, Gunnarsson TS, Moller A, Sigurdsson GH. Acute respiratory distress syndrome: nationwide changes in incidence, treatment and mortality over 23 years. Acta Anaesthesiol Scand 2013;57:37–45.

Khemani, R. G. et al. Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study. Lancet Respir. Med.7, 115–128 (2018).

Marco R, Gordon R, Thompson T, et al. Acute respiratory distress syndrome: The Berlin definition. JAMA. 2012; 307 (23): 2526– 2533.

Moss M, Mannino DM. Race and gender differences in acute respiratory distress syndrome deaths in the United States: an analysis of multiple-cause mortality data (1979- 1996). Crit Care Med 2002;30:1679–1685.

CDC National Center for Health Statistics. Mortality Medical Data System [updated 2015 November 6; accessed 2016 February 18]. Available from: http://www.cdc.gov/nchs/nvss/ mmds.htm

Ando K, Doi T, Moody SY, Ohkuni Y, Sato S, Kaneko N. The effect of comorbidity on the prognosis of acute lung injury and acute respiratory distress syndrome. Intern Med 2012;51:1835-40.

Saguil A& Fargo M. Acute Respiratory Distress Syndrome: Diagnosis and Management. Am Fam Physician. 2012;85(4):352-358.

Zambon M, Vincent JL. Mortality rates for patients with acute lung injury/ARDS have decreased over time. Chest 2008;133:1120-7.

Schouten, L. R. et al. Incidence and mortality of acute respiratory distress syndrome in children: a systematic review and meta- analysis. Crit. Care Med.44, 819–829 (2016).

Mangku, G., Senapathi, T.G., Wiryana, I.M., Sujana, I.B., Sinardja, K. 2010. Buku Ajar Ilmu Anestesia dan Reanimasi. Jakarta: PT Indeks Permata Puri Media.

Koh Y. Update in Acute Respiratory Distress Syndrome. Journal of Intensive Care. 2014;2:2.

Piantadosi CA,Schwartz DA. The acute respiratory distress syndrome. Ann Intern Med 2004; 141:460-70.

Muhardi, Mulyono I, Kristanto S. Aspek fisiologi ventilasi mekanis. Dalam: Muhaimin M, ed. Penatalaksanaan Pasien di Intensive Care Unit. Jakarta: Sagung Seto; 2001.p.29-36.

Amin Z. Acute Respiratory Distress Syndrome. In: Dahlan Z, Amin Z, Soeroto AY, editors. Tatalaksana Penyakit Respirasi dan Kritis Paru. Bandung: PERPARI (Perhimpunan Respirologi Indonesia); 2013.

Piantadosi CA, Schwartz DA. The acute respiratory distress syndrome. Ann Intern Med 2004; 141:460-70.

Muhardi, Mulyono I, Kristanto S. Aspek fisiologi ventilasi mekanis. Dalam: Muhaimin M, ed. Penatalaksanaan Pasien di Intensive Care Unit. Jakarta: Sagung Seto; 2001.p.29-36.

Bellani G, Laffley JG, Fan E, Brochard L, Esteban A, Gattinoni L, et al. Epidemiology, Pattens of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. JAMA. 2016; 315(8): 788-800.

ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, et al. Acute respiratory distress syndrome: The Berlin definition. JAMA 2012;307:2526-33.

Acute respiratory distress syndrome (ARDS). In: Brown KK, Lee-Chiong T, Chapman S, Robinson G, et al. Oxford American Handbook of Pulmonary Medicine. Oxford:Oxford University Press; 2009.p.585-8.

Johnson B, Mattay A, Elizabeth R. Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment. Journal Of Aerosol Medicine And Pulmonary Drug Delivery. 2010; 4(23): 243–252.

Amin Z, Purwoto J. Acute Respiratory Distress Syndrome (ARDS). In: Sudoyo AW, Setiyohadi B, Alwi I. Buku Ajar Ilmu Penyakit Dalam. Balai Penerbit FK UI; 2009. Hal: 4072-4079.

Downloads

Published

2021-06-30

Issue

Section

Jurnal Kedokteran Methodist