Jurnal Kedokteran Methodist

The Impact of a High-Fat Diet on Blood Glucose Levels

2026-03-09T11:40:00+07:00

Background: Diabetes mellitus (DM) sufferers in the world and even in
Indonesia are expected to continue to increase, especially type 2 DM
(DMT2). DMT2 often occurs in people who are obese, the cause of obesity
is often consuming foods that contain a lot of fat. Hyperlipidemia plays a
role in the pathogenesis of pancreatic β-cell dysfunction.
Research method: This study is an experimental laboratory study with a
pretest-posttest only controlled group design, using male white rats
(Rattus norvegicus) with a sample size of 30 divided into 6 groups, namely
the normal group, the negative control group, the positive control group,
the group given a high fatty diet (HFD). The independent variable is HFD,
while the dependent variable is blood sugar levels. Data were analyzed
using the Anova test.
Results: Giving HFD of 4 ml/day for 4 weeks has not been able to increase
KGD to hyperglycemic, this is thought to be because the HFD was not
given for long enough so that insulin resistance had not occurred in the
test animals.
Conclusion: Based on the results of the study, it was concluded that giving
HFD for 4 weeks still could not increase KGD in male white mice to
become hyperglycemic

The Incidence of Pulmonary Tuberculosis in HIV/AIDS Patients at Deli Serdang Regional General Hospital, 2013–2015

2026-03-09T11:15:44+07:00

Background: In 2010, the number of TB patients rose to 330,000 and in
2012, the number of TB patients is quite sharp, ie 583,000 people. TB is
the number one killer among infectious diseases and ranking third in the
list of top ten diseases in Indonesia which causes about 100,000 deaths
annually, or in a day occurred 300 deaths due to TB.
Methods: This study is a descriptive and cross sectional study conducted
at the Medical Records Regional General Hospital Deli Serdang years
2013-2015 total of 49 samples were selected with a total sampling
technique.
Results: Based on the research that has been done, the highest age group
with pulmonary tuberculosis in people with HIV / AIDS is as much as
32.65% of 25-30 years, by sex more dominant male is 79.59%, based on
the most common residence is outside city field as much as 83.67%, the
highest frequency based on the self- employed work is as much as 38.77%,
the highest frequency of risk factors based on sex is as much as 71.42%
and the highest frequency based on CD4 count is <200 as much as
91.83%.
Conclusion: Based on this study concluded that the incidence of
pulmonary TB in people with HIV / AIDS are still very high, the highest in
the age group 25-30 years of age and male gender, the dominant
occupation were self-employed, the highest risk factor was sexual relations
with CD4 count <200.

Tingkat Pengetahuan, Sikap Dan Tindakan Siswa-Siswi Sekolah Menengah Atas Terhadap Acquired-Immunodeficiency Syndrome

2021-11-15T15:00:11+07:00

Background: The problem of HIV/AIDS is a major problem that threatens Indonesia and many other countries around the world. Currently there is not any country free from HIV/AIDS. Since the beginning of the HIV/AIDS became epidemic, nearly 78 million people in all over the world have been infected with HIV and about 39 million people have died from HIV. WHO estimates that 0,8% of people worldwide aged 15-49 years live with HIV.

Method: The purpose of this study is to determine the level of knowledge, attitude, and action in SMA Negeri 1 Kabanjahe against AIDS. This research uses descriptive method with cross sectional approach. Samples are students of class X & XI IPA counted 136 people with slovin formula, where respondents obtained by using simple random sampling technique. Data collection uses questionnaires.

Results: The result of the research indicates that knowledge is good as 87 people (64,0%), with female respondents has good knowledge level of 45 people (33,1%), and based on the most source of information is school as many as 60 people (44,1%). The result of attitude test is good as many as 78 people (57,4%) and result of action test is enough counted 69 people (50,7%).

Conclusion: Based on this research can be concluded that students of class X & XI IPA in SMA Negeri 1 Kabanjahe have knowledge level, good attitude and enough action against AIDS.

The Relationship Between Soil-Transmitted Helminths (STH) Infection and the Stunting Incidence in Toddlers at the Kedai Durian Community Health Center, Medan, Johor, in 2023

2026-03-09T11:57:32+07:00

Background:
Worldwide, around 1 in 4 toddlers experience stunting. Stunting can cause
disorders in the form of stunted brain growth and immune system
disorders in toddlers. Malnutrition at an early age is found to occur in the
first 1000 days of life can increase the risk of infant and child mortality. It
is known that chronic STH infection can cause stunting in children.
Purpose: this study was to determine whether there is a relationship
between Soil Transmitted Helminths (STH) infection and the incidence of
stunting in toddlers at the Kedai Durian Health Center, Medan Johor in
2023.
Research Method: this was carried out in an analytical observational
manner with an approach using a cross-sectional design, which is only
momentary or sees the relationship between soil transmitted helminths
infection and the incidence of stunting in toddlers at the Kedai Durian
Health Center, Medan Johor in 2023 when the study was taking place. The
sampling technique used purposive sampling. Which is to obtain a sample
of 35 respondents based on inclusion and exclusion criteria.
Results: from this study, the most respondents were children infected with
STH worms, as many as 19 respondents (54.3%), and those who were not
infected were 16 respondents (45.7%), it was obtained that the most
children who were stunted were 17 respondents (48.6%), and those who
were not stunted were 18 respondents (51.4%). and There is a relationship
between STH worm infection and stunting with (chisquare count 10.493>
chisquare table (0.05(1)) 3.841, P value 0.01 and RP (3.8). [95% CI 1.37 -
11.28]. From these results, it was also found that children who suffer from
STH infection have a prevalence of stunting 3.8 times more than those who
are not infected with STH, so that STH infection is a high risk factor for
stunting in toddlers.
Conclusion: The results of the study found a relationship between STH
infection and the incidence of stunting

Gambaran Tingkat Pengetahuan Orang Tua tentang Demam Berdarah Dengue (DBD)

2021-11-15T12:29:23+07:00

Background: Dengue Hemorrhagic Fever (DHF) is one of the most common public health problems in Indonesia. Dengue Hemorrhagic Fever is an infectious disease caused by dengue virus. In 2015, there were recorded 126,675 DHF patients in 34 provinces in Indonesia, and 1,229 of them died. The number is higher than the previous year, which is as many as 100,347 people with DHF and as many as 907 patients died in 2014.

Method: This research is a descriptive study with a large sample of 95 respondents with the location of research in Merdeka Village, Medan New District, Medan City. The study began on June 22 - July 04, 2017 and data was collected through the distribution that have validation.

Results: The results showed that of the 95 respondents, majority 40 people (42.1%), had sufficient knowledge about Dengue Hemorrhagic Fever (DBD), 37 people (42.1%), had good knowledge about DBD and 18 people (18.9%)
had less knowledge about DBD.

Conclusion: Based on this research, it can be concluded that generally levelof parent knowledge about DBD including enough category. Parents who have a good knowledge of the source of information from health workers counseling.

Antihyperglycemic Effect of Polyherbal Tea From Moringa oleifera, Cymbopogon citratus, and Stevia rebaudiana Leaves in Alloxan and HFD-Induced Mice (Mus musculus)

2026-03-09T11:44:17+07:00

Diabetes Mellitus (DM) is a disease with metabolic disorders characterized by chronic
hyperglycemia and disorders of carbohydrate, fat, and protein metabolism due to insulin
secretion disorders. In general, DM patients require pharmacotherapy such as injected
insulin or oral antidiabetic drugs. Pharmacological treatment is relatively expensive and
needs to consider its efficacy and safety. Therefore, this study explores natural sources such
as medicinal plants. The aim of this study was to determine the antihyperglycemic effect of a
combination of boiled moringa leaves, lemongrass leaves and stevia leaves on mice (Mus
musculus) induced by alloxan. In this study, 25 mice were divided into 5 groups. The mice
will undergo adaptation for 7 days and then given HFD for 30 days. After 30 days, the mice
will be given alloxan 170 mg/kgBW for 3 days to induce DM. After DM was successfully
induced in mice, polyherbal tea combination of moringa leaves, lemongrass leaves and stevia
leaves was made and given, then continued with evaluation blood glucose, blood glucose
percentage, body weight, body weight percentage, index lee and liver organ index. The group
given herbal tea combination of moringa leaves (Moringa oleifera), lemongrass leaves
(Cymbopogon citratus) and stevia leaves (Stevia rebaudiana) with a concentration of 3.6
mg/mL showed a better decrease in KGD and %KGD compared to other treatment groups.
The decrease in BB, %BB and lee index was better in the group given a combination of
Moringa leaves (Moringa oleifera), Lemongrass leaves (Cymbopogon citratus) and Stevia
leaves (Stevia rebaudiana) with a concentration of 7.2 mg/mL. The decrease in the liver
organ index was also better seen in the group given a combination of Moringa leaves
(Moringa oleifera), Lemongrass leaves (Cymbopogon citratus) and Stevia leaves (Stevia
rebaudiana) with a concentration of 7.2 mg/mL. The group given herbal tea combination of
Moringa leaves (Moringa oleifera), Lemongrass leaves (Cymbopogon citratus) and Stevia
leaves (Stevia rebaudiana) with a concentration of 3.6 mg/mL reduced BG and BG
percentage, while the group given herbal tea combination of Moringa leaves (Moringa
oleifera), Lemongrass leaves (Cymbopogon citratus) and Stevia leaves (Stevia rebaudiana)
with a concentration of 7.2 mg/mL reduced BW, BW percentage, Lee index, and hait organ
index.

The Relationship Between Knowledge and Education Levels of Pregnant Women and the Regularity of Antenatal Care Visits at Tigapanah Community Health Center in 2024

2026-03-09T11:36:12+07:00

Background: Maternal and prenatal mortality remain serious health
issues, primarily due to behaviors and a lack of understanding regarding
healthcare, particularly Antenatal Care (ANC). The irregularity in
prenatal check-ups is influenced by factors such as the educational level
and knowledge of pregnant women.
Objective: To analyze the relationship between knowledge and educational
level of pregnant women with the regularity of prenatal check-ups at
Tigapanah Health Center.
Methods: This study employed a quantitative approach with a cross-
sectional design. The sample consisted of 77 pregnant women selected
through purposive sampling. Data were collected using a validated and
reliable questionnaire, and analyzed using the Chi-Square statistical test.
Results: The results from a total of 77 samples indicate a significant
relationship between knowledge and the regularity of prenatal check-ups
(p = 0.002). The educational level also showed a significant relationship
with the regularity of prenatal check-ups (p = 0.001).
Conclusion: There is a significant relationship between knowledge and
educational level with the regularity of prenatal check-ups.
Keywords: Knowledge, Educational Level, Pregnant Women, Regularity
of Prenatal Check-Ups, ANC

PENGARUH HIPERKOLESTROLEMIA TERHADAP FUNGSI KOGNITIF PADA PASIEN LANSIA DI PUSKESMAS SIMALINGKAR MEDAN

2023-03-13T16:04:22+07:00

Background: of the study. Damage to the structure and function of the brain can lead to a decline and impaired cognitive function. This cognitive impairment can be caused by increasing age and risk factors such as dyslipidemia, hypertension, diabetes and cerebral blood vessels.

Methods: This study used a cross-sectional design. The research population is all the elderly who are in the working area of the Simalingkar Health Center in 2022 as many as 500 people. The sample size is 66 people. The sampling technique was carried out using a consecutive sampling technique. Hypercholesterolemia data collection is based on medical record data, while cognitive impairment uses a mini mental status examination questionnaire. Analysis of research data using univariate and bivariate with Chi Square test.

Results: showed that the majority of the elderly experienced hypercholesterolemia as many as 50 people (76.9%), and cognitive function in the elderly mostly in the normal category as many as 41 people (56.9%). There was no correlation between hypercholesterolemia and cognitive function in the elderly (p = 0.231 > 0.05).

Conclusion: Hypercholesterolemia is not associated with cognitive function in the elderly.

Gambaran Diagnostik Dan Penatalaksanaan Pasien Penyakit Paru Obstruksi Kronik

2021-11-15T12:46:19+07:00

Background: World Health Organization (WHO), Indicate in 1990 occupy 6th order as the leading cause of death and will occupy 3rd order after cardiovascular disease and cancer.In Indonesia estimated 4,8 million patients with prevalence 5,6%.

Method: This research was conducted by using descriptive research design with cross sectionall approach. The number of samples is 80 people withsimple random sampling technique.

Results: Based on the result of research from 80 samples of patients obtained most age ≥60 years ie 50 patients (62,5%),the most of gender is male 69 patient (86,3%),the most of clinical symptoms is shortness of breath 42 patient (52,5%),the most of smokers status is active smoker 58 patient (72,5%), the most of job is entrepreneur 30 patient (37,5%),the most of examination support is radiology 50 patient (62,5%), the most of management is bronchodilator 35 patient (43,7%) and the most of mortality rate was in the ICU room 5 patient (50%).

Conclusion: The result showed with Chronic Obstructive Pulmonal Disease the most treated was male patiens with age ≥65 years, the most of job is entrepreneur, which have a history of smoking with clinical symptoms of shortness breath and cough phlegm, the most of used examintaion support is radiology and the most of management is bronchodilator. Choronic Obstructve Pulmonal Disease management is excellent with fewer deaths.

The Relationship Between Myopia and Hypertension in Open-Angle Glaucoma Patients at Methodist Hospital in 2023

2026-03-09T11:48:06+07:00

Background: Glaucoma is the second leading cause of global blindness
after cataract. Glaucoma is thought to occur due to increased intraocular
pressure (IOP) causing changes in the optic nerve and field of vision.
Objective: To find out whether there is a relationship between
hypertension and myopia in open angle glaucoma patients at Methodist
Hospital in 2023.
Method: This research was conducted in an analytical observational
manner with an approach using a cross sectional design, namely only for a
moment or looking at the relationship between Myopia and Hypertension
in Open Angle Glaucoma Patients at Methodist Hospital in 2023 at the
time the research took place with medical record data of 74 samples based
on inclusion and exclusion criteria. .
Results: From the results of this study, it was found that there was a
relationship between myopia and open angle glaucoma with p – value =
0.000 (<0.05). There is a relationship between hypertension and open
angle glaucoma with p – value = 0.016 (<0.05).
Conclusion: There is a relationship between hypertension and myopia in
open angle glaucoma patients