LEUKEMIA

Abstract

Leukemia is a malignant disease of blood cells originating from the bone marrow, characterized by the proliferation of white blood cells with the manifestation of abnormal cells in the peripheral blood. Acute leukemia is divided into acute lymphocytic leukemia (ALL) and acute myelocytic leukemia (AML). Acute leukemia is a malignant disease that often occurs in children. Leukemia is a malignant disease of blood cells characterized by uncontrolled proliferation of leukocytes with the manifestation of abnormal cells. Leukemia is a malignant blood cell disease characterized by irregular and uncontrolled proliferation of leukocytes with the manifestation of abnormal cells in the peripheral blood. However, the main cause of leukemia is largely unknown, it is thought to be a combination of genetic factors and environmental exposure. Specifically, the risk factors for acute lymphoblastic leukemia (ALL) are: The cause of acute lymphocytic leukemia is unknown, but could be related to ionizing radiation, cytotoxic drugs, viral infections, chromosomal changes or exposure to chemicals. Patients with cases of acute leukemia have prognostic factors which can be influenced by various things such as initial leukocyte count, treatment, transfusion, and cardioprotection such as anthracyclines which have a relationship with cardiotoxicity which is related to factors namely gender, exposure at a young age, and very high cumulative doses of anthracyclines.