Anti-Dyslipidemia Effects Of Psidium guajava L.
DOI:
https://doi.org/10.46880/ijbhm.v1i1.868Keywords:
Psidium guajava, Dyslipidemia, HypercholesterolemiaAbstract
Backgrounds:Dyslipidemia is a clinical condition characterized by an increase in the plasma concentration of triglycerides and/or total cholesterol or its fraction relative to a reference value that is considered normal. These changes include hypertriglyceridemia due to increased synthesis of very low-density lipoprotein (VLDL), reduced triglyceride hydrolysis and/or hypercholesterolemia, due to accumulation of cholesterol-rich lipoproteins, such as low-density lipoprotein (LDL). One of the treatments for dyslipidemia besides using conventional therapy can also be done with traditional medicine or herbal medicine such as guava (Psidium guajava L.). Psidium guajava L. contains lycopene and9-oxo-ODA which has potential as an anti-dyslipidemic.
Methods: This paper uses a literature study or literature review of research articles. Search articles through Google Scholar and Pubmed with keywords used Psidium guajava L. and Dyslipidemia or Hypercholesterolemia. The criteria for articles used in the last 5 years are from 2017 to 2021.
Results: Based on the literature search, there were5studies related to the effect ofPsidium guajava L. on dyslipidemia in the obesity rat model, where all studies were tested on experimental animals.
Conclusion: Based on the literature study, it was found thatPsidium guajava L.is an alternative in the treatment of dyslipidemia which has a fairly effective effect of lowering blood cholesterol (LDL and Triglycerides) levels.
References
Sugondo, S. 2006. Obesitas. Dalam: Sudoyo A.W., Setiyohadi B., Alwi I., Simadibrata M., SetiatiS., editor. Buku Ajar Ilmu Penyakit Dalam. Edisi keempat. Jakarta: Pusat Penerbitan Ilmu Penyakit Dalam FKUI:p.1941-1947.
Winarsi H, Siwi P M, Agus P, 2011, Profil lipid, peroksidasi lipid dan status inflamatif wanita, Jurnal Kesehatan Masyarakat Nasional, Vol 5, No 5, 212-217
.
Murray, C.J.L. 2014. Nearly One-third of the World’s Population is Obese or Overweight, New Data Show. Institue For Health Metrics and Evaluation.
Kemenkes, 2013, Riset Kesehatan Dasar (RISKESDAS), Badan Penelitian dan Pengembangan Kesehatan, Kementrian Kesehatan RI,Hal 225-226.
Rohit Gundamaraju, Sartaj Banu Mulaplli, Dr. Ramesh C. 2012. Evaluation of Anti-Obesity Activity of Lantana camara Var Linn. by Progesterone Induced Obesity on Albino Mice. International Journal of Pharmacognosy and Phytochemical Research. 4(4):213-218.
Putri, S. R. Obesitas sebagai Faktor Resiko Peningkatan Kadar Trigliserida Obesity as Risk Factor of Higher Triglyceride Level. Majority.2015; 20(07); 78.
Hastuty, Y. D. Perbedaan kadar kolesterol orang yang obesitas dengan orang yang non obesitas. Jurnal Kedokteran Dan Kesehatan Malikussaleh.2015; 47–56.
Wurdianing, I., Nugraheni, S. A., & Rahfiludin, Z. Efek ekstrak daun sirsak (Annona muricata Linn) terhadap profil lipid tikus putih jantan (Rattus Norvegicus). Jurnal Gizi Indonesia. 2014;3(1); 7–12.
Adeneye AA, Olagunju JA. Preliminary hypoglycimic and hypolipidemic activities of the aqueous seed extract of carica papaya linn in wistar rats. J. Biology and Medicine [serial online]. 2009 [cited 2013 Jan 15]; 1(1):1-10. Available from: http:// biolmedonline.com/Articles/vol1_1_1- 10.pdf.
Diarti MW, Tatontos EY, Jiwintarum Y, Mianti AS. 2018. Efek Tepung Biji Melon (Cucumis Melo l.) Terhadap Kadar Kolesterol Total Hewan Coba Tikus Putih Jantan (Rattus Norvegicus) Galur Wistar. Jurnal Kesehatan Prima Volume : 12, No.2. Halaman : 151 – 161. URL : http://jkp.poltekkesmataram.ac.id.
Pandanwangi S. dan Oktaviani D. 2018. Uji efektivitas suspense kombinasi ekstrak kulit buah terong ungu (Solanum melongena L.) dan daun jambu biji (Psidium guajava L.) sebagai penurun kadar kolesterol pada tikus putih (Rattus novergicus). Vol 1 No 2 (2018): PRAEPARANDI: Jurnal Sains dan Farmasi.
Rahman M.A., Hamdani I., Thristy I.,Chalil MJA. 2019. Perbandingan efektivitas jus buah tomat (Lycopersicum esculent mill.) dengan jus buah jambu biji merah (Psidium guajava L.) terhadap penurunan kadar kolesterol total pada tikus putih jantan yang diinduksi kuning telur. JURNAL ILMIAH SIMANTEK. Vol. 3 No. 3
Putri MENC. dan Pranitasari N. 2018. Pengaruh Pemberian Ekstrak Jambu Biji (Psidium guajava) Terhadap Kadar Trigliserida Darah Tikus Putih (Rattus norvegicus) Jantan Galur Wistar Yang Diinduksi Deksametason. HTMJ Volume 16 nomer 1 ; 2018.
Mamun, Abdullah & Faruk, Md & Rahman, Md & Nahar, Kamrun & Kabir, Fariha & Alam, Md & Subhan, Nusrat. (2019). High Carbohydrate High Fat Diet Induced Hepatic Steatosis and Dyslipidemia Were Ameliorated by Psidium guajava Leaf Powder Supplementation in Rats. Evidence-based Complementary and Alternative Medicine. 2019. 12. 10.1155/2019/1897237.
Brito, A., Lima, G. M., Farias, L. M., Rodrigues, L., Carvalho, V., Pereira, C., Frota, K., Conde-Júnior, A. M., Silva, A., Rizzo, M., Fonseca, C., Moura, R. C., Santos, R., Leite, J., Santos, M., Nunes, P., Arcanjo, D., & Martins, M. (2019). Lycopene-Rich Extract from Red Guava (Psidium guajava L.) Decreases Plasma Triglycerides and Improves Oxidative Stress Biomarkers on Experimentally-Induced Dyslipidemia in Hamsters. Nutrients, 11(2), 393. https://doi.org/10.3390/nu11020393
Maryanto S, Fatimah S, Sugiri, Marsono Y. Efek pemberian jambu biji merah terhadap produksi SCFA dan kolesterol dalam caecum tikus hiperkolesterolemia. AGRITECH. 2013;33 (3):334-339.
Maryanto S, Fatimah S, Sugiri, Marsono Y. Efek pemberian jambu biji merah terhadap produksi SCFA dan kolesterol dalam caecum tikus hiperkolesterolemia. AGRITECH. 2013;33 (3):334-339.
Downloads
Published
Issue
Section
License
Copyright (c) 2021 International Journal of Biomedical Herbal Medicine
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
