Effect Of Ethanol Extract Jackfruit (Artocarpus Heterophyllus Lam.)To Decrease Blood Sugar Levels In Wistar Female White Rats With Streptozotocin-Induced Gestational Mellitus Diabetes
DOI:
https://doi.org/10.46880/ijbhm.v1i1.736Keywords:
Gestational Diabetes Mellitus, Jackfruit Seed Ethanol ExtractAbstract
Background: Hormonal and metabolic changes during pregnancy cause the pregnancy to be diabetogenic, in which GDM tends to become heavier during pregnancy and will facilitate the occurrence of various complications. DMG mothers approximately 1.7% can cause perinatal mortality, 4.3% give birth to children by surgery, 7.3% give birth to children whose birth weight is more than 4.5 kg and 23.5% can cause cases of dystocia. shoulder during labor.
Methods: The study was conducted using a literature review method that focuses on the results of writing related to the effects of the Jackfruit Seed (Artocarpus heterophyllus Lam.) ethanol extract on female Wistar rats with gestational diabetes mellitus induced by Streptozotocin by browsing accredited journal sites such as Google Schoolar, Google, and Pubmed, in the period 2016-2021.
Conclusion: Based on the research conducted, there was an effect of giving ethanol extract of jackfruit seeds (Artocarpus heterophyllus Lam.) to decrease blood sugar levels in female wistar rats with gestational diabetes mellitus induced by streptozotocin
References
Ministry of Health of the Re-public of Indonesia, "The need for early detection to prevent and reduce the risk of diabetes," The need for early detection to prevent and reduce the risk of diabetes, 2016, [Online]. Availa-ble: www.depkes.go.id.
J. Tandi, JA Claresta, G. Ayu, and I. Irwan, “Effect of ethanol extract of Kenikir (Cosmos caudatus Kunth.) leaves in blood glucose, cholesterol and histopathology pancreas of male white rats (Rattus norvegi-cus),” Indonesia. J. Pharm. sci-ence. Technol., 2018.
S. Candra, K. DK, And Y. Widodo, "Influence Of Alloxan-Induced Alloxan-Induced Blood Glucose Levels Of Wistar Rat (Averrhoa blimbi L.) J. Doctor. Diponegoro, vol. 1, no. 1, p. 105365, 2012.
S. Hardyanti, "Occurrence of Gestational Diabetes Mellitus (DMG) in Sleman Regency, Yogyakarta City," 2019, [Online]. Available: http://digilib2.unisayogya.ac.id/bit-stream/handle/123456789/804/SITI ARDYANTI_1810104215_ naspub.pdf?sequence=1&isAllowed=y.
Sulistiyah, "Supporting Factors of Gestational Diabetes Mellitus Risk in Pregnant Women at BPS Malang Regency," Polytechnic. RS dr. Soepraoen, 2015.
F. Rahmawati, J. Natosba, and J. Jaji, "Gestational Diabetes Melli-tus Screening and Risk Factors Affecting It," J. Sriwij Nursing., 2016.
VA Rahayu, "Antidiabetic activ-ity test of kenikir (cosmos cau-datus h. BK) leaf ethanol extract against alloxan-induced male wistar rats," 2018, [Online]. Available: http://repository.unsri.ac.id/837/1/RAMA_48201_08061381419073_0003077102_0008038802_01_front_ref.pdf (accessed Sep.17,2020).
D. Dwitiyanti, A. Rachmania, K. Efendi, T. Tri Atmojo, and Y. Yeni, “Potential Of Jackfruit (Artocarpus heterophyllus L.) Fruit Installing Alfa-Glucosidase Receptors In Vi-zotogestational Induced Seeds Of Diabetes Mellitus Rats and In Silico," Pros. Kolok. Dr. and Semin. Has. researcher. Grant, 2019, doi:10.22236/psd/11118-13065.
Gissen Aj. Covino BG, Gregus J. Differential sensitivities of mammalian nerve fibers to local anesthetic agents. Anesthesiology 1980;53:467-74.
Johnson MD, Burger GA, Mushlin PS, et al. Reversal of bupivacaine epidural anesthesia by intermittent epidural injections of crystalloid solutions. Anesth Analg 1990;70:395-9.
Sitzman BT, DiFazio CA, Playfair PA, et al. Reversal of lidocaine with epinephrine epidural anesthesia using epidural saline washout. Reg Anesth 2001;26(3):246-251.
Katircioglu K, Ozkalkanli MY, et al. Reversal of prilocaine epidural anesthesia using epidural saline or Ringer’s Lactate washout. Reg Anesth 2007;32(5):389-392.
Brock-Utne JG, Macario A, et al. Postoperative epidural injection of saline can shorten postanesthesia care unit time for knee arthroscopy patients. Reg Anesth 1998;23(3):247-251.
Cousins M, et al. Epidural Neu-ral Blockade. Neuronal blockade. 3rd ed. New York: JB Lippincott, 1998:244-291.
Chan V, Nazarnia S, et al. The impact of saline flush of the epidural catheter on resolution of epidural anesthesia in volunteers: A dose-response study. Anesth Analg 1999;89:1006-10.
Gissen D, Leith DE. Transient decreases in respiratory rate following epidural injections. Anesthesiology 1985;62:822-4.
Higuchi H, Adachi Y. Kazama T. Effects of epidural saline injection on cerebrospinal fluid volume and velocity waveform. A magnetic resonance imaging study. Anesthesiology 2005;102:285-92.
Downloads
Published
Issue
Section
License
Copyright (c) 2021 Universitas Methodist Indonesia
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
