The Effect Of Princess Shame Leaves Ethanol Extract On Vitiligo

Authors

  • Defi Universitas Methodist Indonesia
  • Endy Julianto Universitas Methodist Indonesia

DOI:

https://doi.org/10.46880/ijbhm.v1i1.735

Keywords:

Vitiligo, Ethnomedical, Mimosa Pudica

Abstract

Background: Vitiligo is a skin disease caused by the destruction of melanocytes with depigmented macular characteristics, multifactorial predisposing factors, and precipitating factors such as trauma, sunburn, stress, and systemic disease. Mimosa Pudica has bioactive compounds that are efficacious for healing wounds, repairing cell tissue, stopping bleeding, asthma, diabetes, jaundice, leprosy, hydrocele, hemorrhoids, fistulas, scrofula, and conjunctivitis.

Method: Based on the results of several studies, the technique of collecting & analyzing the cream of Mimosa Pudica leaf extract was by evaluating the cream of the Mimosa Pudica leaves, testing the pH by dissolving the cream product which was diluted using aquadest and then measured with a pH meter. The production of the Mimosa Pudica leaf extract was done by maceration using 96% ethanol.

Results: Mimosa Pudica extract succeeded in preserving salak fruit, increasing the regeneration and proliferation of liver cells, overcoming hypopigmentation skin disease, and also inhibiting melanosis in shrimp.

Conclusion: Mimosa Pudica (Mimosa pudica L.) The five parts of the plant (i.e. panchang) - leaves, flowers, stems, roots, and fruit belong to the category of powerful antioxidants used as medicine in ethnomedical systems of care.

 

Author Biographies

Defi, Universitas Methodist Indonesia

Student of Masters Program in Biomedical Sciences, Faculty of Medicine

Endy Julianto, Universitas Methodist Indonesia

Department of Parasitology, Faculty of Medicine

References

Raven, Peter H, Evert Ray, F. Eichhorn, Susan E. (January 2005) section 6. Physiology of seeds plants: 29. Plant nutrition and soils biology of plants (7th edition). New York: WH Freeman and company page no. 639.

Prasad GC, et al., J.Res.Ind. Med., 1975, 10(4), 37.

Azmi, L., Singh, MK, & Akhtar, AK (2011). Pharmacological and biological overview on Mimosa Pudica Linn. int. J. of Pharm. & Life Sci., 2(11), 1226-1234.

Pendit, PACD, Zubaidah, E., & Sriherfyna, FH (2016). Physical chemical characteristics and antibacterial activity of starfruit leaf extract (Averrhoa bilimbi L). Journal of Food and Agroindustry, 4(1), 400-409.

Thoa, NTL, Nam, PC, & Nhat, DM (2016). Antibacterial activities of the extracts of Mimosa Pudica L. an in-vitro study. International Journal on Advanced Science Engineering Information Technology, 5(5), 358-361.

Lu, Z., Nie, G., Belton, PS, Tang, H., & Zhao, B. (2006). Structure–activity relationship analysis of anti oxidant ability and neuro protective effect of gallic acid derivatives. Neurochemistry International, 48, 263-274.

R. Halder, S. Taliaferro and Vitiligo, Fitzpatrick's dermatology in general medicine, New York: McGraw-Hill Inc., 2008.

E. Nicolaidou, C. Antoniou, A. Miniati, E. Lagogianni, A. Matekovits, A. Stratigos and Et al, "Childhood-and later-onset vitiligo have diverse epidemiologic and clinical characteristics.," J Am Acad Dermatol, vol . 66, no. 6, pp. 954-8, 2011.

C. Singh, D. Parsad, A. Kanwar and R. Kumar, "Comparison between autologous noncultured extracted hair follicle outer root sheath cell suspension and autologous non cultured epidermal cell suspension in the treatment of stable vitiligo: a randomized study," Br J Dermatol, vol. 169, no. 3, pp. 287-93, 2013.

I. Ozturk, K. Batcioglu, F. Karatas, E. Hazneci and M. Genc, "Comparison of plasma malon dialdehyde, glutathione, glutathione peroxidase, hydro xyproline and selenium levels in patients with vitiligo and helathy control.," Indian J Dermatol , vol. 53, no. 3, pp. 106-10, 2008.

Y. Zhu, S. Wang and A. Xu , "A mouse model of vitiligo induced by monobenzone.,"Experimental Dermatology, vol. 22, p. 482–501, 2013.

Kumar, Shashank et al., 2013. Chemical try and Biological Activities of Flavonoids. India: Department of Bio chemistry University of Allahabad

Adawiyah, R., Soekarto & Jenie, B. (1998). Extraction of Anti-microbial Components from Atung Fruit Seeds. Proceedings of the National Seminar on Food and Nutrition Technology.

Tamilarasi, T., & Ananthi, T. (2012). Phytochemical analysis and anti microbial activity of mimosa Pudica linn. Research Journal of Chemical Sciences. 2(2): 72-74.

Jaya, AM (2010). Isolation and Test of Antibacterial Effectiveness of Saponin Compounds from Mimosa Pudica Root (Mimosa Pudica). (Essay). Maulana Malik Ibrahim State Islamic University (UIN), Malang.

Parhusip, AJN, Friska, E., & Saputra, RD (2010). Potential Antimicrobial Activity of Mimosa Pudica (Mimosa Pudica L.) Extract against Food Pathogenic Microbes. Journal of Food Science and Technology. 8(1): 45-54.

Abirami, SKG, Mani, KS, Devi, MN, & Devi, PN (2014). The Anti microbial Activity Of Mimosa Pudica L. International Journal of Ayurveda and Pharma Research. 2(1): 105-108.

Ranjan, RK, Sathish, K., Seethalakshmi & Rao MRK (2013). Phytochemical Analysis Of Leaves And Roots Of Mimosa Pudica Collected From Kalingavaram,Tamil Nadu. Journal of Chemical and Pharmaceutical Research. 5(5): 53-55.

Fadlian, Hamzah, B. & Abram, PH (2016). Test the Effectiveness of Mimosa Pudica Plant Extract (Mimosa Pudica Linn) as a Natural Preservative of Salak. Chemical Academic Journal. 5(4): 153-158.

Montero, P., Martínez-Álvarez, O., & Gómez-Guillén, MC(2004). Effectiveness of onboard application of 4-hexylresorcinol in inhibiting melanosis in shrimp(Parapenaeus longirostris). Journal Of Food Science, 69(8), 643-647.

Pal, P., Datta, S., Basnett, H., Shrestha, B., Mohanty, JP (2015). Phytochemical analysis of the whole plant of Mimosa Pudica (Linn.). UJPSR., 1(1), 1-9.

Lakshmibai, R., Amirtham, D., & Radhika, S. (2016). Preliminary phytochemical analysis and antioxidant activities of prosopis juliflora and Mimosa Pudica L. International Journal Of Scientific Engineering And Technology Research, 4(30), 5766-5770.

Anggraini., Hamidah, A., & Moehammadi, N. (2013). Test the effectiveness of kaffir lime leaf extract (Citrus hystrix DC) and kalamondin orange leaf (Citrus mitis Blanco) as biolarvicides against the death of third instar larvae of Aedes aegypti L. Journal of Scientific Biology, 1(1),1-10.

Otwell, WS, & Marshall, MR (1986). Studies on the use of sulfites to control shrimp melanosis (blackspot): screen alternatives to sulfiting agents to control shrimp melanosis. Florida Seagrant Technical Paper, 46, 1-10.

Downloads

Published

2021-12-12