The Effect of Cyclamate, Stevia, and Sugar on Blood Glucose Levels in White Rats (Rattus norvegicus)
DOI:
https://doi.org/10.46880/ijbhm.v1i2.1354Keywords:
cyclamate, stevia, sugar, blood glucose levelsAbstract
Background: Artificial sweeteners are often used in everyday life because they are relatively cheap and in small amounts can provide many times the sweetness of granulated sugar. The use of artificial sweeteners in the long term can cause various health problems. Therefore, this study aims to determine blood glucose levels given several sweetener solutions so that people are more selective in choosing sweeteners in everyday life.
Method: This type of research is true experimental using posttest-only control group design method. This study used three treatments on white rats (Rattus norvegicus) Wistar strain, namely cyclamate, stevia, and granulated sugar with a dose of 10mg/kgBW for 2 weeks. The data were analyzed using the Saphiro-Wilk test, Kruskal-Wallis test, and Mann-Whitney test.
Results: The results showed that the average blood glucose given cyclamate was 128.33, stevia was 84.43, and sugar was 86.13. While the results of the normality test showed p > 0.05 with a value of 0.107 for cyclamate, 0.126 for stevia, and 0.365 for granulated sugar. The results of the homogeneity test showed p < 0.05 with a value of 0.002 and the Kruskal-Wallis test showed p < 0.05 with a value of 0.003.
Conclusion: there was a significant difference and in the stevia group against the control group and the sugar group against the control group showed p > 0.05 with a value of 0.536 and 0.121, which means there is no significant difference.
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