Effectiveness of Antibacterial Leaf Extract Jatropha curcas Linn with Klebsiella pneumoniae Bacteria

Abstract

Background: This study aims to determine the effectiveness of jatropha leaf extract (Jatropha curcas L) with a concentration of 30%, 50%, 70%, 90%, and 100% against bacteria Klebsiella pneumoniae with amoxicillin-clavulanic acid as a comparison.

Method: The type of research used is true experiment with design posttest only. Antibacterial effectiveness test of leaf extract (Jatropha curcas L) against Klebsiella pneumoniae by agar diffusion/Kirby-Bauer using disc paper in which there is jatropha leaf extract then put into culture media (MHA) this method is useful for observing the diameter of the inhibition zone extract then the results are batch-to-batch good.

Results: The data processing method used in the research trial was Shapiro-Wilk, namely one-way ANOVA to determine the antibacterial effect of jatropha leaf extract and the Least Significant Difference (LSD) test to determine the difference in antibacterial effects between the 2 treatment groups.

Conclusion: From this test, it shows that the research data is normally distributed because p> 0.05 in the statistical test oneway ANOVAshows a value of p= 0.000 (p <0.05), that is, there is a significant difference in the antibacterial effect of jatropha leaf extract (Jatropha curcas L) on bacteria. Klebsiella pneumoniae in the analysis results posthoc LSD showed that there was a significant difference between the extract group and the other extract treatment groups.